Retinoblastoma classification

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Trilateral Retinoblastoma

• Trilateral retinoblastoma is the term that refers to bilateral retinoblastoma associated with an intracranial primitive neuroectodermal tumor in the pineal or suprasellar region. It has a poor prognosis especially when there is leptomeningeal involvement and when the tumor spreads in to subarachnoid space. For dissemination of tumor cells into the sub-arachnoid space, Optic nerve involvement is an important portal.
• The mean length of survival is 9.7 months in patients who undergo treatment and 1.3 months in those who do not after a pineal or sellar mass is detected.