Pheochromocytoma medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
The predominant therapy for pheochromocytoma is surgical resection. Treatment with phenoxybenzamine followed by beta blockers is required before surgery.
Medical Therapy
Any surgical option requires prior treatment with both the non-specific alpha adrenoceptor blocker phenoxybenzamine to counteract hypertension and the beta-1 adrenoceptor antagonist atenolol to reduce cardiac output. Given before surgery, these can also block the effect of a sudden release of adrenaline during tumour removal, which would otherwise endanger the anaethetised patient.
Contraindicated medications
Pheochromocytoma is considered an absolute contraindication to the use of the following medications: