Gastrointestinal stromal tumor risk factors
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Differentiating Gastrointestinal stromal tumor from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
The most potent risk factor in the development of GISTs are age 50-80 and certain genetic syndromes like neurofibromatosis type 1, carney-Stratakis syndrome and familial gastrointestinal stromal tumor syndrome.
Risk factors
- Age-GISTs are more common in people aged 50 to 80
- Genetic syndromes:
- Neurofibromatosis type 1 (or von Recklinghausen disease
- Carney-Stratakis syndrome- People with this rare, inherited condition have an increased risk of GISTs, as well as nerve tumors called paragangliomas.
- Familial gastrointestinal stromal tumor syndrome- It is a rare, inherited condition that leads to an increased risk of developing GISTs.
References