Retinoblastoma staging

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Sowminya Arikapudi, M.B,B.S. [2]Jyostna Chouturi, M.B.B.S [3]

Overview

Retinoblastoma may be classified into several subtypes based on the International Retinoblastoma Staging System (IRSS).

Staging

The International Retinoblastoma Staging System (IRSS)

The International Retinoblastoma Staging System (IRSS) [1]
Staging how much cancer remains after surgery and whether the cancer has spread
Stage 0 The tumor is in the eye only. The eye has not been removed and the tumor was treated without surgery.
Stage I The tumor is in the eye only. The eye has been removed and no cancer cells remain.
Stage II The tumor is in the eye only. The eye has been removed and there are cancer cells left that can be seen only with a microscope.
Stage III
Stage IIIa cancer has spread from the eye to tissues around the eye socket.
Stage IIIb cancer has spread from the eye to lymph nodes near the ear or in the neck.
Stage IV
Stage IVa cancer has spread to the blood but not to the brain or spinal cord. One or more tumors may have spread to other parts of the body such as the bone or liver.
Stage IVb cancer has spread to the brain or spinal cord. It also may have spread to other parts of the body.

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