Ganglioneuroma pathophysiology
|
Ganglioneuroma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Ganglioneuroma pathophysiology On the Web |
|
American Roentgen Ray Society Images of Ganglioneuroma pathophysiology |
|
Risk calculators and risk factors for Ganglioneuroma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Gross Pathology
- Ganglioneuromas are solid, firm tumors that are typically white when seen with the naked eye
- Ganglioneuromas arise in the paravertebral sympathetic chains of the posterior mediastinum (41.5%) or retroperitoneum (37.5%)
- Less common sites include the adrenal gland (21%) and neck (8%)
- Paravertebral ganglioneuromas frequently extend through the neural foramina to involve the epidural space of the spinal canal
- Intradural extramedullary ganglioneuromas are extremely rare[1]
Microscopic Pathology
- Ganglioneuromas are derived from the primordial neural crest cells, which are undifferentiated cells of the sympathetic nervous system.
- Ganglioneuromas are fully differentiated neuronal tumors that do not contain immature elements.
- They are composed of ganglion cells, schwann cells and fibrous tissue.
Videos
{{#ev:youtube|IWng6E9flDA}}
References
- ↑ Pathology of ganglioneuroma. Dr Bruno Di Muzio and Dr Yuranga Weerakkody et al. Radiopaedia 2015. http://radiopaedia.org/articles/ganglioneuroma