Pheochromocytoma classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
Pheochromocytoma can be either benign or malignant and can be localized, regional, or metastatic.
Classification
- Pheochromocytoma can be either benign or malignant and can be localized, regional, or metastatic.
- The most common sites of metastasis for pheochromocytoma are lymph nodes, bones, lungs, and liver.
- Pheochromocytoma is a tumor of the multiple endocrine neoplasia syndrome, type IIA (also known as MEN IIA) and type IIB MEN IIB. The other component neoplasms of that syndrome include parathyroid adenomas, and medullary thyroid cancer. Mutations in the autosomal RET proto-oncogene drives these malignancies[1].