Non-Hodgkin lymphoma classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Non-Hodgkin lymphoma may be classified into 2 Groups: low-grade lymphoma and high-grade lymphoma
Classification of Non-Hodgkin lymphoma
Non-Hodgkin lymphoma may be classified into 2 Groups:[1]
- Low-grade or Indolent lymphoma
- High-grade or Aggressive lymphoma
| Grade | Description |
|---|---|
| Low-grade or Indolent lymphoma | Tend to grow very slowly and there often are few symptoms in the beginning. Because of this, indolent lymphomas tend to widespread by the time they are diagnosed, often involving the bone marrow and spleen. Often treated only when symptoms appear. Can shrink or sometimes seem to disappear with treatment, but they tend to come back. Have a fairly good prognosis. Some indolent lymphomas can change (transform) into more aggressive lymphomas and so need more aggressive treatment. |
| High-grade or Aggressive lymphoma | Grow quickly and tend to spread to lymph nodes or other organs throughout the body. They usually cause symptoms and need treatment right away. Aggressive lymphomas tend to respond well to treatment. Aggressive lymphomas can frequently be successfully treated with intensive chemotherapy treatment. |