DRESS syndrome laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Laboratory Findings
- Laboratory findings of patients with DRESS syndrome usually differ depending on the organ involvement.
- The reported incidence of organ involvement has been highly variable in described cases.
The following table illustrates the incidence of organ involvement in DRESS syndrome:[1][2][3]
Lung || 5% - 10%| Incidence of organ involvement in DRESS syndrome | |
|---|---|
| Organ | Percent of patients with involvement |
| Liver | 60% - 90% |
| Kidney | 40% - 50% |
| Pulmonary | 30% - 40% |
| Cardiac/muscular | 15% -20% |
| Pancreas | 5% - 10% |
The following table illustrates the incidence of common lab abnormalities associated with DRESS syndrome:[1][2][3]
| Incidence of hematologic abnormalities in DRESS syndrome | |
|---|---|
| Abnormality | Percent of patients with abnormality |
| Atypical lymphocytes | 60% - 70% |
| Eosinophilia | 50% - 70% |
| Lymphocytopenia | 40% - 50% |
| Thrombocytopenia | 25% - 50% |
| Lymphocytosis | 25% - 50% |
References
- ↑ 1.0 1.1 Avancini J, Maragno L, Santi CG, Criado PR (2015). "Drug reaction with eosinophilia and systemic symptoms/drug-induced hypersensitivity syndrome: clinical features of 27 patients". Clin Exp Dermatol. doi:10.1111/ced.12682. PMID 26271788.
- ↑ 2.0 2.1 Chen YC, Chiu HC, Chu CY (2010). "Drug reaction with eosinophilia and systemic symptoms: a retrospective study of 60 cases". Arch Dermatol. 146 (12): 1373–9. doi:10.1001/archdermatol.2010.198. PMID 20713773.
- ↑ 3.0 3.1 Cacoub P, Musette P, Descamps V, Meyer O, Speirs C, Finzi L; et al. (2011). "The DRESS syndrome: a literature review". Am J Med. 124 (7): 588–97. doi:10.1016/j.amjmed.2011.01.017. PMID 21592453.