Carcinoid syndrome surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
For qualifying candidates, surgical resection of tumor and chemotherapy (5-FU and doxorubicin) can improve outcomes.
Surgery
Surgery, if feasible, is the only curative therapy. If the tumour has metastasized (most commonly, to the liver), the tumour may be ineligible for surgery (unresectable), though there are many promising treatment modalities, such as radiolabeled octreotide, that are very effective in arresting the growth of the tumours and prolonging survival in patients with liver metastases.
Gastric Carcinoids
- Type I gastric carcinoids smaller than 1 cm are indolent with minimal risk for invasion and can be removed with endoscopic mucosal resection.[1-3] Local surgical excision may be performed for rare larger or invasive tumors, but exceptional cases with large multifocal lesions may require gastric resection.