Osteosarcoma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

On MRI, osteosarcoma is characterized by intermediate intensity of soft tissue and low signal intensity of ossified components on T1. High signal intensity of soft tissue and low signal imtensity of ossified components on T2. Considerable contrast enhancement of solid components on T1 contrast.

MRI

  • MRI is proving essential in accurate local staging and assessment for limb sparing resection, particularly for evaluation of intraosseous tumor extension and soft-tissue involvement.
  • Assessment of the growth plate is also essential as up to 75-88% of metaphyseal tumors do cross the growth plate into the epiphysis.
  • On MRI, signal characteristics of osteosarcoma include:

T1:

  • Soft tissue, non-mineralized component: intermediate signal intensity.
  • Mineralized/ossified components: low signal intensity.
  • Peri-tumoral edema: intermediate signal intensity.
  • Scattered regions of haemorrhage will have variable signal.

T2:

  • Soft tissue non-mineralised component: high signal intensity.
  • Mineralised/ossified components: low signal intensity.
  • peri-tumoral oedema: high signal intensity.

T1 C+ (Gd):

  • Solid components show considerable enhancement.


Images courtesy of RadsWiki

References

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