Osteosarcoma risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Age and height: Data suggest that the risk of osteosarcoma is highest during the teenage "growth spurt." Children with osteosarcoma are usually tall for their age.
Radiation to bones: People who were treated with radiation for another cancer have a higher risk of later developing post-radiation (after radiation) osteosarcoma.
Drugs: Past treatment with anticancer drugs called alkylating antineoplastic agents.
Certain bone diseases: Some bone diseases such as Paget disease of bone, multiple hereditary osteochondromas, fibrous dysplasia, enchondromtosis
Inherited cancer syndromes: Genetic diseases that Predispose to osteosarcoma are: