Osteosarcoma staging

Osteosarcoma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Osteosarcoma from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Staging
History and Symptoms
Physical Examination
Laboratory Findings
Biopsy
X Ray
CT
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Osteosarcoma staging On the Web
Most recent articles
cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Osteosarcoma staging All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Osteosarcoma staging
CDC on Osteosarcoma staging
Osteosarcoma staging in the news
Blogs on Osteosarcoma staging
Directions to Hospitals Treating Osteosarcoma
Risk calculators and risk factors for Osteosarcoma staging

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Staging

• Historically, the Enneking staging system for skeletal malignancies was widely used.
• This system inferred the aggressiveness of the primary tumor by the descriptors intracompartmental or extracompartmental.
• The American Joint Committee on Cancer (AJCC) staging system for malignant bone tumors has updated this staging system, substituting compartmentalization with size.
• The International Union Against Cancer (UICC) uses the TNM system to describe the extent of many solid tumor cancers.

TNM

TNM stands for tumor, nodes, metastasis. TNM staging describes:

• The size and extent of the primary tumor.
• The number and location of any regional lymph nodes that have cancer cells in them
• Whether the cancer has spread or metastasized to another part of the body

TNM staging of osteosarcoma

Stage	Tumor Grade	Tumor Size
IA	Low	<8 cm
IB	Low	>8 cm
IIA	High	<8 cm
IIB	High	>8 cm
III	Any tumor grade, skip metastases
IV	Any tumor grade, any tumor size, distant metastases