Carcinoid syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

The prevalence of carcinoid syndrome is approximately 1.5 per 100,000 individuals worldwide. The incidence of carcinoid syndrome is approximately 15 per 100,000 individuals worldwide. The median age at diagnosis is 61.4 years.

Epidemiology and Demographics

• Carcinoid syndrome is quite rare with a disease prevalence of 15 cases per 1,000,000 people.
• The age-adjusted incidence of carcinoid tumors worldwide is approximately 2 per 100,000 persons.
• The average age at diagnosis is 61.4 years.
• Carcinoid tumors represent about 0.5% of all newly diagnosed malignancies.
• Carcinoid tumors account for 75% of all gastrointestinal endocrine tumors.
• Ovarian carcinoid tumors account for 0.3% of all ovarian tumours and 0.5% of carcinoid tumours.
• Ovarian carcinoid tumors are commonly seen in perimenopausal and postmenopausal women.
• Primary hepatic carcinoid is an extremely rare type of carcinoid tumor, with somewhere between 60-90 cases reported in the literature.
• Thymic carcinoid tumors are more predominant in males, with the male to female ratio around 3:1.