B-cell prolymphocytic leukemia

B-cell prolymphocytic leukemia
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Carlos A Lopez, M.D. [2]

Synonyms and keywords: B-PLL

Overview

B-cell prolymphocytic leukemia is a more aggressive but still treatable form of leukemia. The malignant B cells are larger than average.

Diagnosis exam

• Blood chemistry studies
• Bone marrow aspiration and biopsy
• Complete blood count (CBC)
• CT (CAT) scan
• Cytogenetic analysis
• Immunophenotyping
• Peripheral blood smear
• Physical exam and history (H&P)

Stem cell trasplant

A stem cell transplant is sometimes used to treat people with aggressive prolymphocytic leukemia. Many people with prolymphocytic leukemia are older or may not be in good health, so a stem cell trasplant is often not a suitable option for them. However, it may be an effective option for younger people with prolymphocytic leukemia.

References

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