Gestational trophoblastic neoplasia history and symptoms

Template:Choriocarcinoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

History and Symptoms

Symptoms of gestational trophoblastic disease

• Vaginal bleeding
• Swelling of the abdomen
• With a hydatidiform mole, the abdomen and uterus may grow at a much faster rate than with a normal pregnancy
• Nausea and vomiting or hyperemesis gravidarum
• Passing of tissue resembling a “bunch of grapes” from the vagina
• Absent fetal movement during pregnancy

Rare symptoms of GTD are:

• Headache
• Edema of the hands and feet
• Abdominal or pelvic pain
• Vaginal discharge
• Overactive thyroid gland (hyperthyroidism) that causes:

• Tachycardia
• Sweating
• Shaking
• Heat intolerance
• Fever

Late symptoms

• Hemoptysis
• Dry cough
• Chest pain
• Trouble breathing
• Headache
• Dizziness
• Jaundice
• Paralysis
• Seizure
• Dysarthria and dysphasia
• Vision problems
• Lump in the vagina