Retinoblastoma staging

	Retinoblastoma Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Sowminya Arikapudi, M.B,B.S. [2]Jyostna Chouturi, M.B.B.S [3]

Overview

Retinoblastoma may be classified into several subtypes based on the International Retinoblastoma Staging System (IRSS).

Stage	Features
Stage 0	Patients treated conservatively
Stage I	eye enucleated, completely resected histologically
Stage II	eye enucleated, microscopic residual tumour
Stage III	regional extension
Stage III A	overt orbital disease
Stage III B	preauricular or cervical lymph node extension
Stage IV	Metastatic disease
Stage IV A	haematogeneous metastasis without CNS involvement single lesion multiple lesions
Stage IV B	CNS metastatic involvement prechiasmatic lesion CNS mass leptomeningeal disease