Retinoblastoma staging

Retinoblastoma Microchapters
Home
Patient Information
Overview
Historical perspective
Classification
Pathophysiology
Causes
Differentiating Retinoblastoma from other Diseases
Epidemiology & Demographics
Risk Factors
Screening
Natural history, Complications, and Prognosis
Diagnosis
Diagnostic Study of Choice
History & Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography and Ultrasound
CT scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Retinoblastoma staging On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Retinoblastoma staging All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Retinoblastoma staging
CDC on Retinoblastoma staging
Retinoblastoma staging in the news
Blogs on Retinoblastoma staging
Directions to Hospitals Treating Retinoblastoma
Risk calculators and risk factors for Retinoblastoma staging

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Sowminya Arikapudi, M.B,B.S. [2]Jyostna Chouturi, M.B.B.S [3]

Overview

Retinoblastoma may be classified into several subtypes based on the International Retinoblastoma Staging System (IRSS).

Staging

A number of systems have been devised to stage retinoblastoma, with various end-points, and multiple systems are often used concurrently. The Reese Ellsworth classification is assessed with fundoscopy and aims at predicting the chance of preserving the eye with external beam radiotherapy. . More relevant to radiology practice is the International retinoblastoma classification which predicts overall survival

The International Retinoblastoma Staging System (IRSS)

Stage	Features
Stage 0	Patients treated conservatively
Stage I	eye enucleated, completely resected histologically
Stage II	eye enucleated, microscopic residual tumor
Stage III Stage III A Stage III B	regional extension overt orbital disease preauricular or cervical lymph node extension
Stage IV Stage IV A Stage IV B	Metastasis haematogeneous metastasis without CNS involvement single lesion multiple lesions preauricular or cervical lymph node extension CNS metastatic involvement prechiasmatic lesion CNS mass leptomeningeal disease

See also

• Eye cancer
• Eye examination

Template:Nervous tissue tumors