Glucagonoma surgery
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Glucagonoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Glucagonoma surgery On the Web |
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American Roentgen Ray Society Images of Glucagonoma surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
Surgery is the mainstay of treatment for glucagonoma. The feasibility of surgery depends on the stage of glucagonoma at diagnosis.[1]
Surgery
Surgery is the mainstay of treatment for glucagonoma. The feasibility of surgery depends on the stage of glucagonoma at diagnosis.[1] Single, small lesion in head or tail of pancreas:[1-4]
Enucleation, if feasible.
Large lesion in the head of the pancreas that is not amenable to enucleation:[1-4]
Pancreaticoduodenectomy.
Single, large lesion in body/tail:[1-4]
Distal pancreatectomy.
Multiple lesions:[1-4]
Enucleation, if feasible. Resect body and tail otherwise.
Metastatic disease: lymph nodes or distant sites:[5-12]
Resect when possible. Consider radiofrequency or cryosurgical ablation, if not resectable.
Unresectable disease:[13-22]
Combination chemotherapy. Somatostatin analogue therapy. Necrotizing erythema of glucagonoma may be relieved in 24 hours with somatostatin analogue, with nearly complete disappearance within 1 week.
References
- ↑ 1.0 1.1 Zhang M, Xu X, Shen Y, Hu ZH, Wu LM, Zheng SS (2004). "Clinical experience in diagnosis and treatment of glucagonoma syndrome". Hepatobiliary Pancreat Dis Int. 3 (3): 473–5. PMID 15313692.