Sandbox:risk

INSS stage 3 <365 days of age Unfavorable histology DNA index=1 Irrespective of molecular pathway

Intermediate risk neuroblastoma patients (group 2)

INSS stage 4 <365 days of age Favorable histology DNA index >1 MYCN not amplified

INNS stage 4S <365 days of age Unfavorable histology DNA index=1 MYCN not amplified

Intermediate risk neuroblastoma patients include:

Group 1

Group 2

Patients with stage 3 tumor, <365 days of age, unfavorable histology, DNA index=1, MYCN not amplified Patients with stage 4 tumor, <365 days of age, favorable histology, DNA index >1, MYCN not amplified Patients with stage 4S tumor, <365 days of age, unfavorable histology, DNA index=1, MYCN not amplified

Group 3

Patients with stage 4 tumor, <365 days of age, unfavorable histology, DNA index=1, MYCN not amplified Patients with stage 3 tumor, 365-547 days of age, unfavorable histology, MYCN not amplified Patients with stage 4 tumor, 365-547 days of age, favorable histology, DNA index >1, MYCN not amplified