Retinoblastoma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

The hallmark of retinoblastoma is leukocoria which is an abnormal appearance of the retina as viewed through the pupil, also known as amaurotic cat's eye reflex. A positive family history of retinoblastoma may be present. Less common symptoms of retinoblastoma include deterioration of vision, a red and irritated eye, eye pain, squint, proptosis and fever.

History

Symptoms

The most common finding of retinoblastoma is leukocria which is an abnormal appearance of the retina as viewed through the pupil, also known as amaurotic cat's eye reflex. Some children with retinoblastoma can develop a strabismus, nystagmus, red eye and squint which is commonly referred to as "cross-eyed" or "wall-eyed" (strabismus). Emergency referral to an Opthalmologist is warranted when a child presents with Leukocoria or Strabismus.

Less common symptoms of retinoblastoma include:

  • Deterioration of vision
  • Proptosis
  • Eye pain
  • Squint
  • Fever
  • Symptoms of glaucoma which include:
    • Severe headache
    • Nausea and vomiting
    • Blurred vision
    • Halos around lights

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