Gestational trophoblastic neoplasia history and symptoms
Template:Choriocarcinoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
History
The medical history is a record of present symptoms, risk factors and all the medical events and problems a person has had in the past. The medical history of a person’s family may also help the doctor to diagnose GTD. In taking a medical history, the doctor will ask questions about:
- A personal history of
- Previous pregnancies, including hydatidiform mole (molar pregnancy) and miscarriage
- Previous GTD
- Reproductive factors that may increase the risk of GTD
- A family history of GTD
- Signs and symptoms that may suggest GTD
Symptoms
Early symptoms of gestational trophoblastic disease
- Vaginal bleeding
- Swelling of the abdomen
- With a gestational trophoblastic disease, the abdomen and uterus may grow at a much faster rate than with a normal pregnancy
- Nausea and vomiting or hyperemesis gravidarum
- Passing of tissue resembling a “bunch of grapes” from the vagina
- Absent fetal movement during pregnancy
Rare symptoms of gestational trophoblastic disease
- Headache
- Edema of the hands and feet
- Abdominal or pelvic pain
- Vaginal discharge
- Overactive thyroid gland (hyperthyroidism) that causes:
- Tachycardia
- Sweating
- Shaking
- Heat intolerance
- Fever
Late symptoms gestational trophoblastic disease
- Hemoptysis
- Dry cough
- Chest pain
- Trouble breathing
- Headache
- Dizziness
- Jaundice
- Paralysis
- Seizure
- Dysarthria and dysphasia
- Vision problems
- Lump in the vagina