Retinoblastoma secondary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

Secondary prevention strategies following retinoblastoma include cessation of smoking, reduction in sun exposure, and reduction in exposure to ionizing radiation.

Secondary Prevention

Preventive measures to decrease the risk of secondary malignancies in germinal retinoblastoma patients include

• Cessation of smoking
• Reduction in sun exposure
• Reduction in exposure to ionizing radiation (e.g., x-rays and CT scans)
• Children with familial or bilateral retinoblastoma have an increased risk for secondary malignancies elsewhere in the body such as in the skin, soft tissue and bone. Lifelong monitoring for secondary malignancies is advised in these patients.
• As patients with heritable retinoblastoma are at risk for trilateral retinoblastoma, they may benefit from routine MRI screening during the first five years of life.