Renal oncocytoma pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
On gross pathology, tan or mahogany brown, well circumscribed, and central scar are characteristic findings of the tumor of renal oncocytoma.
Pathogenesis
- Renal oncocytoma is thought to arise from the intercalated cells of collecting ducts of the kidney.[1]
Gross Pathology
- The tumors are tan or mahogany brown, well circumscribed and contain a central scar. They may achieve a large size (up to 12 cm in diameter).[1]
Microscopic Pathology
- An epithelial tumor composed of oncocytes, large eosinophilic cells having small, round, benign-appearing nuclei with large nucleoli with excessive amounts of mitochondria.[2]
References
- ↑ 1.0 1.1 Velasquez G, Glass TA, D'Souza VJ, Formanek AG (1984). "Multiple oncocytomas and renal carcinoma". AJR Am J Roentgenol. 142 (1): 123–4. doi:10.2214/ajr.142.1.123. PMID 6606945.
- ↑ Palmer WE, Chew FS (1991). "Renal oncocytoma". AJR Am J Roentgenol. 156 (6): 1144. doi:10.2214/ajr.156.6.2028856. PMID 2028856.