Renal oncocytoma overview
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Renal oncocytomas are relatively rare, and benign tumors.
Classification
There is no classification system established for renal oncocytoma.
Pathophysiology
On gross pathology, tan or mahogany brown, well circumscribed, and central scar are characteristic findings of the tumor of renal oncocytoma. On microscopic histopathological analysis, oncocytes and large eosinophilic cells are characteristic findings of renal oncocytoma.[1]
Causes
There are no established causes for renal oncocytoma.
Differential Diagnosis
Renal oncocytoma must be differentiated from renal cell carcinoma, metanephric neoplasms, and renal leiomyoma.
Epidemiology and Demographics
The incidence of renal oncocytoma increases with age; the median age at diagnosis is 55 years. The male to female ratio is approximately 2 to 1.[2]
Risk Fctors
There are no established risk factors for renal oncocytoma.
Screening
According to the the U.S. Preventive Service Task Force (USPSTF), there is insufficient evidence to recommend routine screening for renal oncocytoma.[3]
Complications and Prognosis
Common complications of renal oncocytoma include hypertension, hematuria, and abdonimal pain. Prognosis is generally excellent.[4]
Staging
There is no established system for the staging of reanl oncocytoma.
History and Symptoms
Symptoms of renal oncocytoma include hematuria and flank pain.
Physical Examination
Physical examination of patients with renal oncocytoma is usually remarkable for a palpable abdominal mass.
Laboratory Findings
There are no diagnostic lab findings associated with renal oncocytoma.
X Ray
X-ray is rarely done for the diagnosis of renal oncocytoma.
CT Scan
Abdonimal CT scan is helpful in the diagnosis of renal oncocytoma.
MRI
MRI may be helpful in the diagnosis of renal oncocytoma.
Ultrasound
Ultrasound may be helpful in the diagnosis of renal oncocytoma.
Other Imaging Findings
Intravenous pyelogram may be helpful in the diagnosis of renal oncocytoma.
Other Diagnostic Studies
There are no other diagnostic study findings associated with renal oncocytoma.
Biopsy
On biopsy, renal oncocytoma is characterized by oncocytes and large eosinophilic cells.
Medical Therapy
The mainstay of therapy for renal oncocytoma is surgery.
Surgery
Surgery is the mainstay of treatment for renal oncocytoma.
Primary Prevention
There is no established method for prevention of renal oncocytoma.
Secondary Prevention
There are no secondary preventive measures available for renal oncocytoma.
References
- ↑ Palmer WE, Chew FS (1991). "Renal oncocytoma". AJR Am J Roentgenol. 156 (6): 1144. doi:10.2214/ajr.156.6.2028856. PMID 2028856.
- ↑ Renal oncocytoma.Dr Donna D'Souza et al. Radiopaedia.org 2015.http://radiopaedia.org/articles/renal-oncocytoma
- ↑ renal oncocytoma. U.S. Preventive Service Task Force (USPSTF) 2015. http://www.uspreventiveservicestaskforce.org/BrowseRec/Search?s=renal+oncocytoma Accessed on October, 27 2015
- ↑ Lieber MM (1990). "Renal oncocytoma: prognosis and treatment". European Urology. 18 Suppl 2: 17–21. PMID 2226597.