Sandbox:DDx HEENT
- 35-50 yo women
- Painless nodular enlargement in the neck
- Euthyroid state
- Iso-hyperechoic mass with alarge cystic component on U/S
- Surrounding hypoechoic halo
- Spongelike/honeycomb pattern with eggshell coarse calcifications
- Intranodular vascularity
- Heterogeneous iodine uptake on thyroid scan
- Follicles of variable size
- microfollicular architecture
- Unencapsulated
- No nuclear features suggestive of malignancy
- TG-gene
- TPO-gene
- SLC5A5 gene
- SLC26A4 gene
- TSH-R-gene
- DEHAL-1 gene
- DUOX2 gene