Polycythemia vera screening
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Polycythemia vera Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Screening for polycythemia vera by cell-based quantitative assays for JAK2V617F mutation is recommended among patients with erythrocytosis, thrombocytosis, and monocytosis.[1][2]
Screening
Screening for polycythemia vera by cell-based quantitative assays for JAK2V617F mutation assays may be helpful among patients with the following:[1][2]
- Erythrocytosis
- Thrombocytosis
- Splanchnic vein thrombosis
- Unexplained BCR-ABL negative granulocytosis
References
- ↑ 1.0 1.1 The Asco Post. JAK2 and MPL Mutation Screening: What Are the Indications and How to Interpret the Results. http://www.ascopost.com/issues/february-15-2012/jak2-and-mpl-mutation-screening-what-are-the-indications-and-how-to-interpret-the-results.aspx
- ↑ 2.0 2.1 Tefferi A, Noel P, Hanson CA (2011). "Uses and abuses of JAK2 and MPL mutation tests in myeloproliferative neoplasms a paper from the 2010 William Beaumont hospital symposium on molecular pathology". J Mol Diagn. 13 (5): 461–6. doi:10.1016/j.jmoldx.2011.05.007. PMC 3157620. PMID 21723416.