Sandbox:DDx HEENT

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    • Bimodal distribution among young adults and elderly males
    • Localized progressive cervical lymphadenopathy
    • Constitutional symptoms


    • Enlarged, hard, fixed cervical lymph nodes


  • Reed- Sternberg cells
  • Collagen deposition and fibrosis
  • Infiltrating macrophages, eosinophils, and lymphocytes infiltration
  • CD15 and CD30 +ve
  • t(14;18)(q32;q21)
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