Ovarian germ cell tumor surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]

• Stage I Ovarian Germ Cell Tumors
• Standard treatment options:
• Dysgerminomas
• Unilateral salpingo-oophorectomy with or without lymphangiography or computed tomography (CT)
• Unilateral salpingo-oophorectomy followed by observation
• Unilateral salpingo-oophorectomy with adjuvant radiation therapy or chemotherapy
• Other Germ Cell Tumors
• Unilateral salpingo-oophorectomy with adjuvant chemotherapy
• Unilateral salpingo-oophorectomy followed by observation

Stage II Ovarian Germ Cell Tumor

• Standard treatment options:
• Dysgerminomas
• Total abdominal hysterectomy and bilateral salpingo-oophorectomy with adjuvant radiation therapy or chemotherapy.
• Unilateral salpingo-oophorectomy with adjuvant chemotherapy.
• Other Germ Cell Tumors
• Unilateral salpingo-oophorectomy with adjuvant chemotherapy.
• Second-look laparotomy.

Stage III Ovarian Germ Cell Tumors

• Standard treatment options:
• Dysgerminomas
• Total abdominal hysterectomy and bilateral salpingo-oophorectomy.
• Unilateral salpingo-oophorectomy with adjuvant chemotherapy.
• Other Germ Cell Tumors
• Total abdominal hysterectomy and bilateral salpingo-oophorectomy with adjuvant chemotherapy, with or without neoadjuvant chemotherapy.
• Unilateral salpingo-oophorectomy with adjuvant chemotherapy, with or without neoadjuvant chemotherapy.
• Second-look laparotomy

Stage IV Ovarian Germ Cell Tumors Standard treatment options: Dysgerminomas Total abdominal hysterectomy and bilateral salpingo-oophorectomy with adjuvant chemotherapy. Unilateral salpingo-oophorectomy with adjuvant chemotherapy.

Other Germ Cell Tumors

Standard treatment options:

Total abdominal hysterectomy and bilateral salpingo-oophorectomy with adjuvant chemotherapy with or without neoadjuvant chemotherapy. Unilateral salpingo-oophorectomy with adjuvant chemotherapy with or without neoadjuvant chemotherapy.