Essential thrombocytosis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

The incidence of Essential thrombocytosis was estimated to be 0.6-2.5 cases per 100,000 individuals worldwide annually. Though in reality the number may be much more higher attributing the incidental diagnosis of the condition where many go undiagnosed due to lack of routine medical care. The median age at onset is 65-70 years. Worldwide, the prevalence of Essential thrombocytosis is about 24 for every million people in the world. The disease shows a slight female preponderance in the elderly patients while the incidence remains the same in patients who present with ET in their 3rd decade of life.

Epidemiology

Incidence

• The incidence of Essential thrombocytosis was estimated to be 0.6-2.5 cases per 100,000 individuals worldwide annually.
• In reality the incidence may be much more higher attributing the incidental diagnosis of the condition where many go undiagnosed due to lack of routine medical care.

Prevalence

• Worldwide, the prevalence of Essential thrombocytosis is about 24 for every million people in the world..

Age

• ET is usually first diagnosed in the late 50's or early 60's.
• ET has a bimodal presentation in that it presents in people in their 60's while the other peak occurs in the 30's.
• The median age at onset is 65-70 years.

Gender

• Women in their third decade of life are more commonly affected with Essential thrombocytosis than men at same age. The male to female ratio is approximately 1:1.5-2
• Patients in the 6th decade of life usually have same incidence in both men and women.

References

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