Sandbox: DDx Kidney mass

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  • 10-30 yo sickle cell trait patients
  • May have gross hematuria, back/flank pain, weight loss, and fever
  • Palpable renal mass
  • Lymphadenopathy
  • Centrally located infiltrative mass invading the renal sinus
  • Peripheral caliectasis
  • Smaller peripheral satellite nodules
  • Heterogeneous enhancement on CT
  • Heterogeneous echotexture on US

Nonmalignant causes

anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying