Sandbox: DDx Kidney mass
- May have refractory hypertension, palpitations, headache, diaphoresis, anxiety, weight loss, and flank pain
- MEN, von Hippel–Lindau disease, tuberous sclerosis, or neurofibromatosis
- Pallor
- Tachycardia
- Elevated serum catecholamines and metanephrines
- Large, heterogeneous mass on CT
- Areas of necrosis and cystic change
- on CT
- VHL, RET, NF1SDHB and SDHD gene mutation
Nonmalignant causes
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying