Intracerebral metastases medical therapy
Intracerebral metastases Microchapters |
Differentiating Intracerebral Metastases from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Medical Therapy
Symptomatic Treatment
- Corticosteroids are given to limit the effects of peritumoral edema.[1] Hyperosmolar agents (eg mannitol) can be given to decrease ICP and anticonvulsants are given to prevent seizures. Recently, methylphenidate and donepezil have been used to improve cognition, mood and quality of life.
Therapeutic
Radiation Therapy
- The most widely used treatment for patients with multiple brain metastases is whole brain external beam radiotherapy (WBRT).[1]
- Stereotactic radiosurgery is done for smaller masses.