Myxoma historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Maria Fernanda Villarreal, M.D. [2]
Overview
In 1954 Clarence Crafoord, a Swedish cardiovascular surgeon, successfully removed a cardiac myxoma for the first time. This case also represents the first extirpation of a cardiac tumor on cardiopulmonary support.[1]
Historical perspective
In 1951 Prichard described a kind of microscopic endocardial structure of the atrial septum, which was suggested to be related to cardiac myxoma. [2] In the same year, intracardiac myxoma was recognized by angiography for the first time.[3]
In 1954 Clarence Crafoord (1899 – 1984), a Swedish cardiovascular surgeon, successfully removed a cardiac myxoma for the first time. This case also represents the first extirpation of a cardiac tumor on cardiopulmonary support. [1]. Before 1951, cardiac myxoma diagnosis was made only at autopsy. In 1959, the first M-mode echocardiogram was used to diagnose a left atrial myxoma. [4]
In 1999, chromosome mutations 2p16, 12 and 17q22-24 were first identified in the pathogenesis of Cardiac myxoma syndromes (LAMB (lentigines, atrial myxoma, mucocutaneous myxomas and blue nevi) and NAME (nevi, atrial myxoma, mucinosis of the skin and endocrine overactivity)
References
- ↑ 1.0 1.1 Chitwood WR (1992). "Clarence Crafoord and the first successful resection of a cardiac myxoma". Ann. Thorac. Surg. 54 (5): 997–8. PMID 1417305.
- ↑ Amano J, Kono T, Wada Y, Zhang T, Koide N, Fujimori M, Ito K (2003). "Cardiac myxoma: its origin and tumor characteristics". Ann Thorac Cardiovasc Surg. 9 (4): 215–21. PMID 13129418.
- ↑ Bulkley BH, Hutchins GM (1979). "Atrial myxomas: a fifty year review". Am. Heart J. 97 (5): 639–43. PMID 433739.
- ↑ Pinede L, Duhaut P, Loire R (2001). "Clinical presentation of left atrial cardiac myxoma. A series of 112 consecutive cases". Medicine (Baltimore). 80 (3): 159–72. PMID 11388092.