Waldenström's macroglobulinemia physical examination
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mirdula Sharma, MBBS [2]
Overview
Patients with Waldenström's macroglobulinemia usually appear oriented to time, place, and person. Physical examination of patients with Waldenström's macroglobulinemia is usually remarkable for various findings depending on degree of tissue infiltration by malignant tumor cells, hyperviscosity syndrome, and accumulation of paraprotein.[1]
Physical Examination
Patients with Waldenström's macroglobulinemia usually appear oriented to time, place, and person. Physical examination of patients with Waldenström's macroglobulinemia is usually remarkable for various findings depending on degree of tissue infiltration by malignant tumor cells, hyperviscosity syndrome, and accumulation of paraprotein.[1]
General
HEENT
CNS
- Peripheral neuropathy - distal, symmetric, and sensorimotor
Respiratory
- Pleural effusion - in 3-5% of patients
Cardiovascular system
- Congestive heart failure - occurs in few patients presenting with displaced apical impulse, S3 gallop, distended jugular vein, rales at lung auscultation, and peripheral edema.