Intracerebral metastases differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Differential Diagnosis

Intracranial metastases must be differentiated from:

• Glioblastoma multiforme
• Primary CNS lymphoma
• Stroke
• Epilepsy
• Radiation necrosis
• Brain abscess
• Herpes simplex encephalitis

Gallery

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  _{CT scan of a 60 year old patient who developed left-handed weakness which improved with corticosteroids and neurological examination revealing left pronator drift and left sided arm and leg weakness demonstrates right frontoparietal hyperdense intra-axial lesion that enhances in post contrast study. Small surrounding vasogenic edema and no significant mass effect is observed.}

• 

  _{CT scan of a patient with known (histologically confirmed) small cell carcinoma of the lungs demonstrates multiple cystic cerebral metastases.}

• 

  _{Ct scan without contrast of the patient with known metastatic breast cancer, complaining of headache, demonstrates a solitary right frontal lobe mass with extensive surrounding edema. The mass has it's epicenter close to the grey white matter junction.}

• 

  _{Ct scan with contrast of the patient with known metastatic breast cancer, complaining of headache, demonstrates a solitary heterogenously enhancing right frontal lobe mass with extensive surrounding edema. The mass has it's epicenter close to the grey white matter junction.}

• 

  _{Postcontrast CT image of brain for a 60 year old male patient with metastatic bronchogenic carcinoma presenting with altered mental status and headache of recent onset demonstrating enhancing intra-axial lesion.}

• 

  _{Noncontrast CT of a 36 year old female, a known case of esophageal cancer, presenting with headache and right sided hemiparesis, demonstrates a cystic lesion (37 x 31 mm) in the left high frontal lobe with significant perilesionalvasogenic edema causing mass effect in the form of sulcal effacement and subfalcine herniation.}

• 

  _{Post contrast CT of a 36 year old female, a known case of esophageal cancer, presenting with headache and right sided hemiparesis, demonstrates a ring-enhancing cystic lesion (37 x 31 mm) in the left high frontal lobe with significant perilesionalvasogenic edema causing mass effect in the form of sulcal effacement and subfalcine herniation.}

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