Neurofibroma surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
Surgery
Localised neurofibroma/Diffuse neurofibroma
- Localised and diffuse lesions may be treated surgically.
- Neurofibromas that infiltrate between nerve fascicles are unable to be separated from the parent nerve, therefore, deep-seated lesions are often managed conservatively.
- Local recurrence after excision is uncommon and malignant transformation is rare.
Plexiform neurofibroma
- Plexiform neurofibroma is found in approximately 30% of patients with neurofibromatosis type 1 (NF1).
- due to multiplicity of lesions, unless debilitating symptoms are present, treatment of patients with NF1 is often non-surgical.
- Plexiform neurofibromas are particularly difficult to resect, often leading to incomplete resection.
- Recurrence after resection is frequent