Ovarian germ cell tumor laboratory tests

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]

Overview

The laboratory findings associated with ovarian germ cell tumor are the following: serum lactate dehydrogenase (LDH), human chorionic gonadotropin (HCG), CA-125, and alpha-fetoprotein (AFP).

Ovarian germ cell tumor Laboratory Findings

The tumor marker associated with ovarian germ cell tumor subtypes are as follows

Ovarian germ cell tumor subtype	Tumor markers expressed
Dysgerminoma	Serum lactate dehydrogenase (LDH) Human chorionic gonadotropin (HCG)
Endodermal sinus tumor or yolk sac tumors	Alpha-fetoprotein (AFP)
Embryonal Carcinoma	HCG, AFP
Teratoma	Rarely produce tumor markers- AFP and CA-125
Choriocarcinoma	HCG