Ovarian germ cell tumor classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]

Overview

Ovarian germ cell tumor may be classified into 7 subtypes based on histology.

Classification

Ovarian germ cell tumor may be classified into 7 subtypes based on histology:

• Dysgerminoma
• Endodermal sinus tumor (rare subtypes are hepatoid and intestinal)
• Embryonal carcinoma
• Polyembryoma
• Choriocarcinoma
• Teratoma:

• Immature
• Mature:

• Solid

• Cystic:

• Dermoid cyst (mature cystic teratoma)
• Dermoid cyst with malignant transformation

• Monodermal and highly specialized:

• Struma ovarii
• Carcinoid
• Others (e.g., malignant neuroectodermal and ependymoma)

• Mixed forms