Myxoma classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Maria Fernanda Villarreal, M.D. [2]
Overview
Cardiac myxomas are classified by the WHO histological classification of tumors of the heart, as "Benign tumors and tumor-like lesions" and categorized into a type of pluripotent mesenchymal tumor. According to the World Health Organization, cardiac myxoma is a neoplasm composed of stellate to plump, cytologically bland mesenchymal cells set in a myxoid stroma. [1] [2][3]
Classification
Based on the location and biological behavior of symptoms, cardiac myxomas may be classified into two groups: typical and atypical. In typical cases, cardiac myxomas are almost always single, and there is a striking predilection for the left atrium, with approximately 75-86% occurring there.
In atypical cases, presentation is usually early and multicentricity is more common and they are more frequently located on the right side of the heart (38%), or in the left ventricle (5%). [4] [3] There is also recurrence after surgical excision (12%–22%) and an association with other conditions, such as the Carney complex.
Distribution:
- Atria (95%)
- left (75%)
- right (20%)
- Ventricles (5%)
References
- ↑ Amano J, Nakayama J, Yoshimura Y, Ikeda U (2013). "Clinical classification of cardiovascular tumors and tumor-like lesions, and its incidences". Gen Thorac Cardiovasc Surg. 61 (8): 435–47. doi:10.1007/s11748-013-0214-8. PMC 3732772. PMID 23460447.
- ↑ Wold LE, Lie JT (1980). "Cardiac myxomas: a clinicopathologic profile". Am. J. Pathol. 101 (1): 219–40. PMC 1903582. PMID 7446701.
- ↑ 3.0 3.1 Grebenc ML, Rosado de Christenson ML, Burke AP, Green CE, Galvin JR (2000). "Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation". Radiographics. 20 (4): 1073–103, quiz 1110–1, 1112. doi:10.1148/radiographics.20.4.g00jl081073. PMID 10903697.
- ↑ Cardiac Myxoma.Radiopedia.URL http://radiopaedia.org/articles/cardiac-myxoma accessed on November 13,2015