Sandbox: Bone DDx

Revision as of 15:03, 23 November 2015 by Haytham Allaham (talk | contribs)
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  • 30-50 yo patients
  • Unerupted teeth
  • Oral ulcers
  • Painless mandibular mass
  • Lower jaw crepitus on palpation
  • Facial deformity


  • Multilocualted, expansile "soap-bubble" lesion, with well demarcated borders on X ray
  • Mixed solid and cystic pattern on MRI
  • Thick irregular wall, often with papillary solid structures projecting into the lesion on MRI
  • Tall columnar cells with a palisaded nuclei and reverse polarization
  • Subnuclear vacuolization
  • Giant cells
  • Subepithelial hyalinization


  • BRAF V600E mutations