Sandbox: Bone DDx

Revision as of 18:49, 23 November 2015 by Haytham Allaham (talk | contribs)
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  • 50-70 yo males
  • Deep, achy, dull pain
  • Night time bone pain
  • Limited range of joints motion
  • Pathologic fracture
  • Palpable lump or local mass effect
  • Large calcified lesions
  • Thin and expanded bone
  • Multiple surface erosions
  • Cortical thickening


  • Lytic intralesional calcification
  • Endosteal scalloping
  • Moth eaten appearance
  • Cortical remodelling, thickening and periosteal reaction


Bi-nucleation. Hypochromatic enlarged nuclei. Infiltration of lamellar bone ("invasion") Increased cellularity

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