Myelodysplastic syndrome differential diagnosis
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Differentiating Myelodysplastic syndrome from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
The differential diagnosis is that of anemia, thrombocytopenia, and/or leukopenia. Usually, the elimination of known etiologies of cytopenias, along with a dysplastic bone marrow, is required to diagnose a myelodysplastic syndrome.
Myelodysplastic syndrome differential diagnosis
Differential Diagnosis (for dysplasia)
- Arsenic, Lead, Benzene, Xylene, petroleum, Agent Orange (Vietnam Veterans).
- Congenital Dyserythropoietic anemia
- HIV
- Vitamin B12 / folate
- Parvovirus
- Alcohol abuse
- Prior chemotherapy (eg. melphalan, mustard, chlorambucil, busulfan, cyclophosphamide).
- Radiation (with or without chemotherapy).