Linitis plastica history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
Symptoms of linitis plastica may include dyspepsia, nausea, vomiting, early satiety, loss of appetite, weight loss, abdominal discomfort and sometimes diarrhea.[1][2] [3] A positive family history of diffuse gastric cancer may be present if it is the hereditary form of the disease.
History and symptoms
- Diffuse gastric adenocarcinoma or linitis plastica remains asymptomatic for a long time before diagnosis. Therefore, when a patient presents with symptoms, the disease is usually in an advanced stage.[3]
- Thickening and rigidity of the stomach wall makes the process of digestion difficult and the patient may complain of nausea, vomiting, bloating and sometimes diarrhea.
- Patients may develop non specific symptoms like:[1][2][3]
- A family history of linitis plastica may be present in patients with the hereditary diffuse adenocarcinoma, which is autosomal dominantly inherited.
References
- ↑ 1.0 1.1 Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273. Accessed on December 8, 2015.
- ↑ 2.0 2.1 Linitis plastica. Wikipedia. https://en.wikipedia.org/wiki/Linitis_plastica Accessed on December 8, 2015
- ↑ 3.0 3.1 3.2 Jafferbhoy S, Shiwani H, Rustum Q (2013). "Managing Gastric Linitis Plastica: Keep the scalpel sheathed". Sultan Qaboos Univ Med J. 13 (3): 451–3. PMC 3749031. PMID 23984032.