Biliary cystadenoma and cystadenocarcinoma overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Biliary cystadenomas are uncommon unilocular or multilocular cystic neoplasms that may occur within the liver (infrequently found in the extrahepatic biliary tree and gallbladder).

Although biliary cystadenomas are benign tumors, they may recur after excision and have potential to develop into biliary cystadenocarcinoma.

Classification

There is no classification system established for biliary cystadenoma and biliary cystadenocarcinoma.

Pathophysiology

On gross pathology, biliary cystadenoma is unilocular or multilocular cystic lesion filled with fluid. Cystic fluid may be clear and mucinous. On microscopic histopathological analysis, presence of biliary-type epithelium wall, occasional papillary projections, and ovarian-like stroma are characteristic findings of biliary cystadenoma.