Adenocarcinoma of the lung CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]

Overview

Chest CT scan may be helpful in the diagnosis of adenocarcinoma of the lung. Finding on CT scan suggestive of adenocarcinoma of the lung is a lung nodule with a rounded or irregular region of increased attenuation.

CT Scan

• Chest CT scan may be helpful in the diagnosis of adenocarcinoma of the lung.

• Sometimes it is impossible to radiographically distinguish between other histological lung cancer types.

• Finding on CT scan suggestive of adenocarcinoma of the lung is a lung nodule with a rounded or irregular region of increased attenuation measuring less than 3 cm. The amount of attenuation can further classify the nodules as either ground glass, sub-solid, or solid.

• Histologically, the ground-glass attenuation corresponds to a lepidic growth pattern and the solid component correspond to invasive patterns. Hence the preinvasive category of adenocarcinoma in situ, minimally invasive adenocarcinoma, and lepidic predominant invasive adenocarcinoma is often seen as ground glass nodule or sub-solid nodule with a predominant ground-glass component. On the other hand, the remaining invasive subtypes of adenocarcinoma is usually a solid nodule but may also subsolid and only occasionally seen as ground glass nodule.

• Invasive mucinous adenocarcinoma subtype can have a variable appearance ranging from consolidation, air bronchograms or seen as multifocal subsolid nodules or masses.

References

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