Ameloblastoma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

Symptoms of ameloblastoma include mouth sores, painless swelling, loose teeth, facial deformity, swelling and numbness of the jaw, pain surrounding the teeth or jaw, and pain associated with the tissue growth, if ameloblastoma spreads to the sinus cavities and floor of the nose.

History

Clinically, ameloblastoma appears as an aggressive odontogenic tumour, often asymptomatic and slow growing, with no evidence of swelling. It can sometimes cause symptoms such as swelling, dental malocclusion, pain and paresthesia of the affected area. It spreads by forming pseudopods in marrow spaces without concomitant resorption of the trabecular bone. As a result, the margins of the tumor are not clearly seen on radiographs or during surgery and the tumor frequently recurs after inadequate surgical removal. The appearance of septae on the radiograph usually represents differential resorption of the cortical plate by the tumor and not actual separation of tumor portions. Because of its slow growth, recurrences of ameloblastoma generally present many years and even decades after primary surgery. When treated inadequately, malignant development is a possibility.

Symptoms

Symptoms of ameloblastoma include the following: Lesions occur in the mandible or maxilla. Lesions are more common in the mandible, than in the maxilla. In approximately 80% of the cases, the posterior mandible is involved; in 20% cases, the posterior maxilla is involved.

  • Mouth sores
  • Painless swelling
  • Loose teeth
  • Facial deformity
  • Swelling and numbness of the jaw
  • Pain surrounding the teeth or jaw
  • A thin shell of bone around the tissue may develop due to abnormal growths, which usually cracks upon touch
  • There may be pain associated with the tissue growth, if ameloblastoma spreads to the sinus cavities and floor of the nose

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