Sporotrichosis medical therapy
Sporotrichosis Microchapters |
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Risk calculators and risk factors for Sporotrichosis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alison Leibowitz [2]
Treatment
Form | Primary Line of Treatment | Alternative Treatment | Remarks/Other |
---|---|---|---|
Uncomplicated cutaneous | Itraconazole [200 mg/day] | Itraconazole [200 b.i.d.],
terbinafine [500 b.i.d.], SSKI [increasing doses], fluconazole [400-800 mg/day], or local hyperthermia |
Continue treatment for 2-4 weeks after lesions resolve. |
Osteoarticular | Itraconazole [200 mg b.i.d.] | Limposomal amphotericin B [3-5 mg/kg/day] or deoxycholate amphotericin B [0.7-1 mg/kg/day] until symptom resolution | For a total of 12 months, switch to itraconazole after resolution/end of treatment. |
Pulmonary | Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] | Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole upon symptom resolution | Treat less sever cases with a 12 month regimen of itraconazole. |
Meningeal | Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] | Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole upon symptom resolution | Precise length of amphotericin B treatment varies. Suppressive treatment with itraconazole is necessary. |
Dissimated | |||
Sporotrichosis in pregnant women | |||
Sporotrichosis in Children |