Splenic marginal zone lymphoma differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

Splenic marginal zone lymphoma must be differentiated from other diseases such as chronic lymphocytic leukemia, follicular lymphoma, and mantle cell lymphoma.^[1]

Splenic marginal zone lymphoma must be differentiated from other diseases such as:^[1]


Differential Diagnosis	CD5	CD10	Cyclin-D1

Splenic marginal zone lymphoma	Negative	Negative	Negative
Chronic lymphocytic leukemia	Positive	Negative	Negative
Follicular lymphoma	Negative	Positive	Positive
Mantle cell lymphoma	Positive	Negative	Positive

↑ ^1.0 ^1.1 Splenic marginal zone lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf57e3e27c3994bd5327/. Accessed on January 14, 2016