Mycosis fungoides pathophysiology
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Cutaneous T cell lymphoma Microchapters |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Pathophysiology
The disease is an unusual expression of T-cells, a part of the immune system. These T-cells are skin-associated, meaning that they biochemically and biologically are most related to the skin, in a dynamic manner. Mycosis Fungoides is the most common type of 'Cutaneous T cell lymphoma' (CTCL). "Sézary's cells" are T-cells that have pathological quantities of mucopolysaccharides. Sézary's disease is sometimes considered a late stage of mycosis fungoides. Sezary syndrome and Mycosis Fungoides are T-cell lymphomas whose primary manifestation is in the skin.
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