Sandbox: Kaposi 2

• The optimal therapy for Kaposi's sarcoma depends on multiple factors which include:

• The anatomical location of the tumor
• The specific variant of Kaposi's sarcoma
• The rate of distribution and progression of Kaposi's sarcoma lesions
• The patients clinical presentation
• The efficacy and potential side effects of therapy
• The presence or absence of HIV infection
• The degree of immune suppression,
• The presence of other comorbidities
• The degree of host immune competence
• The preference and prognosis of the patients

• Management strategies varies depending on the specific variant of Kaposi's sarcoma such as:

• Classic Kaposi's sarcoma managemenet may range from no treatment to either radiotherapy, local therapeutic interventions, or surgical excision.
• Iatrogenic Kaposi's sarcoma management focuses on modifying immunosuppressive therapy in addition to local therapeutic interventions.
• Endemic Kaposi's sarcoma is primarily manage by systemic chemotherapy
• There is no curative treatment for epidemic Kaposi's sarcoma; the mainstay management is HAART therapy which aims for the palliation and control of Kaposi's sarcoma progression.